Leaders in Research Peptides

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PAL-AHK (Topical)

£109.08

Buy PAL-AHK 50mg (Topical)

PAL-AHK Topical is a research peptide studied for its potential to support collagen production, defend against oxidative stress, and assist in skin repair deep within the dermal layers.

Topical peptides are for research use only.

Buy 10 and get 10% Discount

Buy PAL-AHK Topical Europe 200mg

This product is intended for research purposes only. To be used by trained professionals only.

PAL-AHK Topical, or Palmitoyl Tripeptide-3, is a synthetic peptide built from alanine, histidine, and lysine, enhanced by the strategic inclusion of a palmitoyl group. This modification improves its lipophilicity, helping it reach deeper into the skin’s dermal layers, where it interacts with cell receptors and may influence gene expression. [1]

Research shows this peptide engages dermal fibroblasts, encouraging protein synthesis and mechanisms linked to skin regeneration. It has gained attention for its role in supporting the structural scaffolding of the skin, largely by promoting collagen type activity critical for elasticity and firmness.


Potential Benefits of PAL-AHK Topical Peptide

PAL-AHK Topical is under investigation for its ability to reduce the impact of oxidative stress. This stress is caused by free radicals, UV radiation, and environmental pollutants. This protective action helps preserve skin integrity. [2]

It may also limit the premature formation of wrinkles and fine lines. Such capabilities are vital. They help counter the harmful effects of environmental pollutants on skin and the health of hair follicles.

Its possible effects on DNA repair factor signaling plus pathways related to cell survival and death make it a strong candidate. It fits studies targeting skin cell proliferation and extracellular matrix support. These functions matter. They help maintain skin texture, tone, and overall health. They also affect skin cell receptors involved in repair and cell growth.

The peptide’s interaction with vascular endothelial growth factor (VEGF) has been seen in lab settings. It may help form new blood vessels. That boosts nutrient flow and supports wound healing especially in damaged or aged skin. This is a major contributor. It restores tissue vitality and supports the growth of new hair in stressed areas.

Though studied mainly for skin, PAL-AHK has also been explored for hair follicle development. It may help reduce inflammation, spark growth factor signaling, and aid issues tied to androgenetic alopecia, hair loss, hair regeneration, and hair density. [3]

Its dual-action profile regenerative and defensive makes it a key player in advanced, research-driven skincare. Its design allows stable integration and deeper reach. This makes it a strong choice for studying skin cell behavior, protein synthesis, and amino acid-related repair. [4]

As a meticulously designed synthetic peptide, PAL-AHK shows what an innovative peptide can do. It supports both skin and hair health through the peptide’s dual functionality.

 This product is intended strictly for research purposes only. It is not for human use.


How Should PAL-AHK Topical Peptide Be Stored?

PAL-AHK should be kept in a cool, dry environment between 2°C and 8°C, shielded from light and moisture. Its meticulously designed structure, including the palmitoyl group, is sensitive to heat and oxidation.

When in solution, store in airtight containers to protect against degradation and maintain accuracy in testing scenarios. Proper handling ensures valid results when researching effects on skin regeneration, collagen synthesis, deeper dermal activity, and the broader realm of skincare ingredients.

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References:

[1] Mortazavi SM, Mohammadi Vadoud SA, Moghimi HR. Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective. Bioimpacts. 2024 Apr 28;15:30071.

[2] He B, Wang F, Qu L. Role of peptide-cell surface interactions in cosmetic peptide application. Front Pharmacol. 2023 Nov 13;14:1267765.

[3] Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018 Jul 7;19(7):1987.

[4] Pyo HK, Yoo HG, Won CH, Lee SH, Kang YJ, Eun HC, Cho KH, Kim KH. The effect of tripeptide-copper complex on human hair growth in vitro. Arch Pharm Res. 2007 Jul;30(7):834-9.

Molecular formula: C31H56N6O5
Molecular weight: 592.8


ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.

DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Europe Direct Peptides website: https://europe.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.


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